اختلال عملکرد میتوکندریایی ۲۰۱۳
Mitochondrial Dysfunction 2013

1. Front Cover

2. Mitochondrial Dysfunction

3. Copyright Page

4. Dedication

5. Table of Contents

6. Contributors

7. Preface

8. Introduction: Criteria for Assessing Normal and Abnormal Mitochondrial Function

9. Chapter 1. Mitochondrial Isolation from Liver and Kidney: Strategy, Techniques, and Criteria for Purity

10. Chapter 2. Mitochondrial Isolation from Brain: Strategy, Techniques, and Criteria for Purity

11. Chapter 3. Intact Rat Brain Mitochondria from a Single Animal: Preparation and Properties

12. Chapter 4. Study of Skeletal Muscle Mitochondrial Dysfunction

13. Chapter 5. Small-Scale Preparation of Skeletal Muscle Mitochondria and Its Application in the Study of Human Disease

14. Chapter 6. Metabolie Control Analysis as a Method to Assess Mitochondrial Dysfunction

15. Chapter 7. Commentary: Methods for in Vivo Assessment of Mitochondrial Function

16. Chapter 8. Noninvasive Assessment of Mitochondrial Function by Breath Analysis Using Ketoisocaproic Acid

17. Chapter 9. Absorption Spectroscopy for Assessment of Mitochondrial Function in Vivo

18. Chapter 10. Analysis of Mitochondrial Function by Carbon-13 Nuclear Magnetic Resonance Spectroscopy in Intact Tissues

19. Chapter 11. Phosphorus-31 Nuclear Magnetic Resonance Spectroscopy in the Study of Mitochondrial Metabolism

20. Chapter 12. Mitochondrial Dysftinctíon in Ischemic Organs

21. Chapter 13. Screening for Mitochondrial Cytopathy: The Subanaerobic Threshold Exercise Test

22. Chapter 14. Morphometry of Mitochondria: Size, Internal Structure, Subcellular Distribution, and Three-Dimensional Reconstruction

23. Chapter 15. Megamitochondria

24. Chapter 16. Redox Status and Mitochondrial Inner Membrane Permeability

25. Chapter 17. Assessment of Mitochondrial Glutathione as a Measure of Cell Injury

26. Chapter 18. Experimental Manipulation of Mitochondrial Glutathione Concentrations

27. Chapter 19. Determination of Flux, Activity, and Activity State of Mitochondrial α-Keto Acid Dehydrogenase Complexes

28. Chapter 20. Regulation of Oxygen Uptake in the Liver Lobule by Oxygen Tension

29. Chapter 21. Generation of Reactive Oxygen Metabolites and Oxidative Damage in Mitochondria: Role of Calcium

30. Chapter 22. Fatty Acid Metabolism and Reye's Syndrome

31. Chapter 23. Antioxidative Function of Vitamin Ε and Ubiquinols

32. Chapter 24. Mitochondrial NADPH

33. Chapter 25. Long-Chain Acyl-CoA Metabolism by Mitochondrial Carnitine Palmitoyltransferase: A Cell Model for Pathological Studies

34. Chapter 26. Identification of Mitochondrial Dysfunction at Coupling Site I: Loss of Activity of NADH-Ubiquinone Oxidoreductase during Myocardial Ischemia

35. Chapter 27. Identification of Mitochondrial Dysfunction at Coupling Site II

36. Chapter 28. Cellular Calcium and Mitochondrial Dysfunction

37. Chapter 29. Chronic Alcoholism and the Mitochondrial F0F1-ATP Synthase

38. Chapter 30. Mitochondrial Pyrophosphate Metabolism in Health and Disease

39. Chapter 31. Toxic Effects of Calcium on Mitochondria

40. Chapter 32. Calcium and the Regulation of Intramitochondrial Dehydrogenases

41. Chapter 33. Use of Fluorescent Probes to Monitor Mitochondrial Membrane Potential in Isolated Mitochondria, Cell Suspensions, and Cultured Cells

42. Chapter 34. Commentary: Genetic Approaches to Mitochondrial DNA Diseases of Oxidative Phosphorylation

43. Chapter 35. Developmental Aspects of Mitochondrial Dysfiinction

44. Chapter 36. Mitochondrial DNA Synthesis

45. Chapter 37. Covalent Binding of Reactive Intermediates of Xenobiotics to Mitochondrial DNA

46. Chapter 38. Mitochondrial DNA Repair and Cell Injury

47. Index