اتصال گیرنده در تحقیقات دارویی ۲۰۲۰
Receptor Binding in Drug Research 2020

1. Cover

2. Half Title

3. Series Page

4. Title Page

5. Copyright Page

6. Dedication Page

7. Series Introduction

8. Foreword

9. Preface

10. Contents

11. Contributors

12. Part I Analysis and Interpretation of Receptor Screening Data

1 Receptor Binding Methodology and Analysis

2 Computer Analysis of Binding Data

15. Part II Receptor Screening Applied to Specific Therapeutic Areas

3 Benzodiazepines and Nonbenzodiazepines

4 Enhancers of Benzodiazepine Binding

5 Convulsant and Anticonvulsant Drug Receptor Binding

6 Neuroleptic Receptor Binding in Drug Research

7 Receptor Binding and Atypical Antidepressant Drug Discovery

8 Central Recognition Sites for Psychomotor Stimulants: Methylphenidate and Amphetamine

9 Opiate Receptor Binding in Drug Research

23. Part III Receptor Interactions with Implications in Multiple Therapeutic Areas

10 Molecular Heterogeneity of Leukotriene Receptors

11 Purinergic Receptors in Mammalian Tissue

12 New Routine Methodology to Study Steroid Hormone Binding Sites in Heterogeneous Tissues

13 Application of Ligand Binding to the Development of New Calcium Antagonists and Activators

14 Muscarinic Cholinergic Receptor Binding

29. Part IV Receptor Applications to Peptides, Growth Factors, and Endogenous Ligands

15 Interferon Receptors: Progress and Prospects

16 The Platelet-Derived Growth Factor Receptor

17 Receptor Screening Assays for Insulin and Other Growth Factors

18 Cholecystokinin Receptor Binding: Its Use in Drug Research and Development

19 Using Radioreceptor Binding Assays to Identify Endogenous Ligands

35. Part V In Vivo and In Vitro Receptor Methodologies for Use in Drug Discovery and Characterization

36. Antidepressants

20 In Vivo Receptor Modifications as a Measure of Antidepressant Potential

21 Antidepressant Interactions with Neurotransmitter Receptors in Vitro: Prediction of Potential Side Effects

22 Altered Responsiveness of the Noradrenergic-Coupled Adenylate Cyclase System in Brain

23 Quantitative Autoradiography in Drug Research: Tricyclic Antidepressants

41. Anxiolytics

24 Characterization of Agonist and Antagonist Interactions at the Benzodiazepine Receptor

43. Cholinergic Agents

25 Receptor Binding Assays for Muscarinic Cholinergic Agonists

45. Index