مقاومت گلیوبلاستوما به شیمی‌درمانی: سازوکارهای مولکولی و راهبردهای معکوس‌سازی نوآورانه ۲۰۲۱
Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies 2021

1. Cover

2. Front Matter

3. Table of Contents

4. Copyright

5. Cover Image Legend

6. Aims and Scope for Series “Cancer Sensitizing Agents for Chemotherapy”

7. About the Series Editor

8. Aims and Scope of the Volume

9. About the Volume Editors

10. Preface

11. Contributors

12. List of Illustrations

13. List of Tables

14. Chapter 1 : Overview of glioblastoma biological hallmarks and molecular pathology

15. Chapter 2 : Past and present drug treatments for glioblastoma

16. Chapter 3 : Investigational new drugs against glioblastoma

17. Chapter 4 : Molecular mechanisms in temozolomide-resistant glioblastoma

18. Chapter 5 : Glioma stem cells and associated molecular mechanisms in Glioblastoma Chemoresistance

19. Chapter 6 : Signaling in the tumor microenvironment of therapy-resistant glioblastoma

20. Chapter 7 : Intratumoral heterogeneity associated with glioblastoma drug response and resistance

21. Chapter 8 : Role of apoptosis, autophagy, and the unfolded protein response in glioblastoma chemoresistance

22. Chapter 9 : Role of multidrug resistance in glioblastoma chemoresistance: Focus on ABC transporters

23. Chapter 10 : Role of mitochondrial reactive oxygen species in glioblastoma drug resistance and strategies for therapeutic intervention

24. Chapter 11 : Glioblastoma cell-induced immunosuppression causing chemoresistance

25. Chapter 12 : Role of cell quiescence in glioblastoma cytotoxic resistance and strategies for therapeutic intervention

26. Chapter 13 : The molecular and cellular effects of radiotherapy-induced microenvironment changes on potential chemoresistance in glioblastoma

27. Chapter 14 : Molecular and cellular mechanisms in recurrent glioblastoma chemoresistance

28. Chapter 15 : Role of long noncoding RNAs in temozolomide-resistant glioblastoma

29. Chapter 16 : Mechanisms of glioblastoma resistance to antiangiogenic agents and reversal approaches

30. Chapter 17 : Treatment and resistance of glioblastoma to CAR T-cell immunotherapies

31. Chapter 18 : On-chip analysis of glioblastoma cell chemoresistance

32. Chapter 19 : Three-dimensional in vitro models to study potentiation of glioblastoma resistance by hypoxia

33. Chapter 20 : Chemoresistance mechanisms in mouse models of glioblastoma

34. Chapter 21 : Therapeutic approaches to overcome temozolomide resistance in glioblastoma

35. Chapter 22 : Understanding signal transduction pathways to overcome targeted therapy resistance in glioblastoma

36. Chapter 23 : Targeting the molecular mechanisms of glioma stem cell resistance to chemotherapy

37. Chapter 24 : Immunotherapy for glioblastoma as a means to overcome resistance to standard therapy

38. Chapter 25 : Role of microRNA therapy in presensitizing glioblastoma cells to temozolomide treatment

39. Chapter 26 : Drug penetration through the blood–brain barrier after radiotherapy: New approaches to bypass glioblastoma chemoresistance

40. Chapter 27 : Nanoparticles beyond the blood-brain barrier for glioblastoma

41. Chapter 28 : Small molecules targeting misfolded mutants of p53 as a rescue strategy to improve glioblastoma chemotherapy

42. Chapter 29 : p53 supplementation as a targeted cancer gene therapy for glioblastoma

43. Index

44. A