مفاهیم در توسعه واکسن ۲۰۱۲
Concepts in Vaccine Development 2012

1. The Need for New Vaccines

1.1 Vaccines as Evolutionary Tools: The Virulence-Antigen Strategy

3. Acknowledgements

4. References

1.2 Economic Perspectives on Vaccine Needs

6. Acknowledgments

7. References

1.3 Future Immunization Strategies – Considerations from the Public Health View

9. References

1.4 The New Pertussis Vaccines

11. References

2. General Principles of Immunology

2.1 Basic Principles of Immunity Against Intracellular Bacteria and Protozoa

14. Acknowledgements

15. References

2.2 Viral Immunity and Vaccine Strategies

17. Acknowledgements

18. References

2.3 Broadly Reactive HLA Restricted T Cell Epitopes and Their Implications for Vaccine Design

20. Acknowledgements

21. References

2.4 Quantitative Considerations in the Design of Vaccination Strategies Against Pathogens Uniquely Susceptible to Cell-Mediated Attack

23. References

2.5 The Impact of the Type 1 and Type 2 T Helper Cell Concept on Novel Vaccine Design with Emphasis on Protection Against Leishmania Parasites

25. Acknowledgements

26. References

3. General Principles of Vaccinology

3.1 Modern Adjuvants. Functional Aspects

29. References

3.2 Biodegradable Microspheres as Vehicles for Antigens

31. References

3.3 Peptide Based Vaccines

33. References

3.4 Recombinant Bacteria as Vaccine Carriers of Heterologous Antigens

35. References

3.5 Genetic Detoxification of Bacterial Toxins

37. References

3.6 Recombinant Virus as Vaccination Carrier of Heterologous Antigens

39. References

3.7 Naked DNA Vaccination

41. References

3.8 Oral Vaccination, Mucosal Immunity and Oral Tolerance with Special Reference to Cholera Toxin

43. Acknowledgements

44. References

4. Specific Vaccination Strategies

4.1 Helicobacter pylori: Pathogenic Determinants and Strategies for Vaccine Design

47. Acknowledgements

48. References

4.2 Malaria Vaccination

50. Acknowledgements

51. References

4.3 Vaccination Against Schistosomiasis: Concepts and Strategies

53. References

4.4 AIDS Vaccination

55. References

4.5 Vaccination Therapy Against Autoimmune Diseases

57. Acknowledgements

58. References

59. Contributors